Síndrome de POEMS: a propósito de un caso

POEMS syndrome is a disease of unknown pathogenesis. The acronym stands for the disease’s main clinical manifestations: polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy and skin disorders. Recent studies suggest association genetic mutations with immunoglobulin λ. We report case 56-year-old male patient 10-month picture, whose initial signs symptoms were lower limb edema hypertrichosis, followed by gastrointestinal symptoms, inguinal lymphadenopathy paresthesia. emphasize importance this case, given limited reports at national level no reported cases in department La Libertad, long time it takes to diagnose such disease.